Photo：010-62890160
| Biological Activity | |
| Synonyms | APC |
| Chemical Name | (3R,4R,4aR,6aS,8R,9R,11aS,11bS)-4,9-bis(hydroxymethyl)-4,11b-dimethyltetradecahydro-8,11a-methanocyclohepta[a]naphthalene-3,9-diol |
| Application | Aphidicolin is a novel tetracyclic diterpene antibiotic and also a DNA synthesis inhibitor in eukaryotes. |
| CAS Number | 38966-21-1 |
| Purity | ≥98.0% |
| Molecular Weight | 338.48 |
| Molecular Formula | C₂₀H₃₄O₄ |
| SMILES | C[C@]12CC[C@H]([C@@]([C@@H]1CC[C@@H]3[C@@]24CC[C@@]([C@H](C3)C4)(CO)O)(C)CO)O |
| Shipping | Gel Pack |
| Storage | Store at -20°C |
| Solubility | |
| DMSO: 50mg/mL methanol: 10mg/mL |
| Product Description | |
Aphidicolin is a diterpene fungal metabolite that blocks the cell cycle at early S-phase. In addition, Aphidicolin is a tetracyclic diterpene antibiotic with antiviral and antimitotic properties. Aphidicolin was first isolated from Cephelosporium aphidicola. Aphidicolin is a specific inhibitor of DNA polymerase α and δ in eukaryotic cells and in some viruses of animal origin. |
